What Is MOTS‑c Peptide?
MOTS-c Peptide (mitochondrial open reading frame of the 12S rRNA‑c) is a naturally occurring mitochondrial‑derived peptide (MDP) encoded within the mitochondrial genome. Unlike traditional peptides, MOTS‑c peptide mimics exercise‑induced metabolic adaptations by regulating cellular energy balance, glucose uptake, and insulin signaling. It has become a focus of cutting‑edge research in metabolic health, aging, and energy regulation.
Key Benefits & Mechanisms
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Supports Glucose Metabolism – Enhances insulin sensitivity and promotes efficient glucose utilization in peripheral tissues.
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Mimics Exercise Effects – Activates AMPK and other metabolic pathways typically stimulated by physical activity.
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Promotes Mitochondrial Biogenesis – Encourages the formation of new mitochondria, supporting cellular energy production.
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Metabolic Homeostasis – Helps maintain balanced energy metabolism, making it relevant for obesity and metabolic syndrome research.
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Age‑Related Metabolic Decline – Studied for its potential role in counteracting age‑associated metabolic dysfunction.
| Unit Size | 5 mg/vial |
| Unit Quantity | 1 Vial |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | 2174.64 |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Appearance | White Powder |
| Peptide Purity | >99% |
| Solubility | >Soluble in water or 1% acetic acid |
| Identity (ESI-MS) | 4963.44±5.1 |
| Source | Chemical Synthesis |
| Storage | Lyophilized MOTS-c is stable at room temperature for 90 days, however it should be stored in a freezer below -8C for any extended period of time. After reconstituting MOTS-c should be refrigerated at temperatures not to exceed 36 F. |
| WARNING | This product is a lyophilized peptide for research use only. This product is NOT for human use and can be harmful if ingested. This product is for research/laboratory use only. This product is NOT in a sterile solution and is NOT to be injected. This product should only be handled by licensed, qualified professionals. If you buy peptides online from us, they are not peptides for bodybuilding. This product is not a drug, food, or cosmetic and should not be misbranded, misused or mislabeled as a drug, food or cosmetic. |












